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Usual Adult Dose for Deep Vein Thrombosis Prophylaxis after Knee Replacement Surgery Prophylaxis of DVT in patients undergoing knee replacement surgery.Prophylaxis of deep vein thrombosis (DVT) in patients undergoing hip replacement surgery, during and following hospitalization.Following the initial phase of thromboprophylaxis in hip replacement surgery patients, continued prophylaxis with 40 mg subcutaneously once a day for 3 weeks is recommended.ĭuration of therapy: Usually 7 to 10 days up to 14 days has been well tolerated in clinical trials. For hip replacement surgery, a dose of 40 mg subcutaneously once a day given initially 12 hours prior to surgery may be considered. Provided that hemostasis has been established, the initial dose should be given 12 to 24 hours after surgery. Usual Adult Dose for Deep Vein Thrombosis Prophylaxis after Hip Replacement Surgeryģ0 mg subcutaneously every 12 hours. Use: Prophylaxis of recurrent myocardial infarction or death in patients with acute STEMI receiving thrombolysis and being managed medically or with PCI, when concurrently administered with aspirin. Usual Adult Dose for Acute Coronary Syndrome If the last subcutaneous dose was given more than 8 hours before balloon inflation, an IV bolus of 0.3 mg/kg should be given. For patients managed by percutaneous coronary intervention (PCI), if the last subcutaneous dose of enoxaparin was less than 8 hours before balloon inflation, no additional dosing is required.All patients should be given oral aspirin therapy (75 to 325 mg once a day unless contraindicated).When given in conjunction with a thrombolytic, enoxaparin should be given between 15 minutes prior and 30 minutes after the start of fibrinolytic treatment.

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Use: Prophylaxis of ischemic complications of unstable angina and non Q wave myocardial infarction, when concurrently administered with aspirin.Īcute ST-Segment Elevation Myocardial Infarction (STEMI):ģ0 mg IV bolus once plus 1 mg/kg subcutaneously once followed by 1 mg/kg subcutaneously every 12 hours (maximum 100 mg for the first two doses only, followed by 1 mg/kg for the remaining doses)ĭuration of therapy: Optimal duration is unknown, but it is likely to be longer than 8 days. Usual duration is 2 to 8 days up to 12.5 days has been well tolerated in clinical trials. Unstable Angina and Non Q Wave Myocardial Infarction:ġ mg/kg subcutaneously every 12 hours in conjunction with oral aspirin therapy (100 to 325 mg once a day)ĭuration of therapy: At least 2 days and until clinical stabilization. Usual Adult Dose for Myocardial Infarction Use: Prophylaxis of deep vein thrombosis (DVT) in medical patients at risk for thromboembolic complications due to severely restricted mobility during acute illness.

Usual Adult Dose for Deep Vein Thrombosis - Prophylaxisĭuration of therapy: Usually 6 to 11 days up to 14 days has been well tolerated in clinical trials.

Inpatient treatment of acute DVT with or without PE when administered in conjunction with warfarin sodium.

Outpatient treatment of acute deep vein thrombosis (DVT) without pulmonary embolism (PE) when administered in conjunction with warfarin sodium.

Average duration is 7 days up to 17 days has been well tolerated in controlled clinical trials.Ĭomments: In both outpatient and inpatient treatments, warfarin sodium therapy should be initiated when appropriate (usually within 72 hours of commencing enoxaparin). Inpatient: 1 mg/kg subcutaneously every 12 hours or 1.5 mg/kg subcutaneously once a day at the same time every day.ĭuration of therapy: At least 5 days and until a therapeutic oral anticoagulant effect has been achieved (INR 2 to 3). Outpatient: 1 mg/kg subcutaneously every 12 hours Usual Adult Dose for Deep Vein Thrombosis

Deep Vein Thrombosis Prophylaxis after Abdominal Surgery.

Deep Vein Thrombosis Prophylaxis after Knee Replacement Surgery.

Deep Vein Thrombosis Prophylaxis after Hip Replacement Surgery.